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What are Bone Marrow Derived Stem Cells?

Bone marrow derived stem cells (BMCs) are stem cells that are found in bone marrow, or the soft tissue inside your bones that create blood cells. Bone marrow has historically been a rich source of not only hematopoietic stem cells, but mesenchymal stem cells as well. These types of stem cells can differentiate into different types of blood cells (hematopoietic cells) and cells present in tissues like bone, cartilage, muscles, and fat (mesenchymal cells). These cells can have many benefits in treating conditions that affect certain areas of the body that are experiencing factors like degeneration, inflammation, and injury, among others. This is because MSCs provide the ability (through noninvasive extraction and processing) to help promote healing, regeneration, and repair of target tissues.

 

How are Bone Marrow Derived Stem Cells Collected?

Bone marrow aspiration, which may seem like a very painful procedure, is completed in a short period of time with little to no discomfort. This procedure produces a small sample of your own bone marrow tissue which can be activated and made ready for injection on the same day. Often, bone marrow derived stem cells can be combined with adipose derived stem cells for increased efficacy. During a consultation, our stem cell experts can ensure you know the specifics of your bone marrow stem cell therapy.

What Can I Expect During This Process?

Our stem cell therapies are performed within the same day at our state-of-the-art, accredited ambulatory facility. During the extraction process, our expert, board-certified providers can ensure that you’re comfortable and relaxed. We use image-guided techniques and technology at this step to ensure that your procedure is quick, efficient, and successful. After the cells are collected and activated, they can either be suspended in platelet-rich plasma derived from your own blood sample, or applied alone to the affected area. After the procedure, you can return home the same day with instructions for a quick and easy recovery.

What Happens After Injection?

After the stem cells are injected into the targeted area through various routes of administration, the cells begin to differentiate into the specific cells and tissues needed to repair and heal your body. Although your expert provider can give you the best idea of what to expect, your timeframe after therapy will be unique to you, since everyone’s body heals at different rates. During this time, you might benefit from platelet-rich plasma techniques to aid this process.

Bone Marrow Derived Stem Cell FAQ's

Are bone marrow and stem cells the same thing?

There are two significant types of stem cells that are present in bone marrow. Hematopoetic stem cells which give way to blood cell lineages and mesenchymal stem cells which are multipotent adult stem cells. These Mesenchymal stem cells can self renew and regenerate with the ability to form multiple tissues including muscle , connective tissue, cartilage, bone and fat.

Are bone marrow cells stem cells?

Both Hematopoetic and Mesenchymal stem cells are found in bone marrow aspirate. MSCs are the most commonly stem cell found in Bone Marrow aspirate. BMA is commonly used for orthopedic conditions like osteoarthritis, joint and muscle injuries , and skin repair. They may also be useful for regeneration of nervous tissue, blood vessel, and the regulation of inflammatory cytokines.

Are bone marrow stem cells multipotent?

Yes, The mesenchymal cells present in the bone marrow aspirate are multipotent , meaning they have the ability to formulate a few different cell types including cartilage, bone, fat, connective tissue, nervous tissue, and blood vessel.

Are MSCs stem cells?

Yes. MSCs are known as Mesenchymal stem cells and are the active form of stem cells used in stem cell therapy for non blood disorder conditions.

Do adults have stem cells?

Yes , Adult stem cells are the most widely used sources of stem cells and can be taken from the patient ( autologous) or from a donor ( allogeneic). Adult stem cells can be derived from many different sources, most commonly adipose (fat) tissue and bone marrow. Some adult postnatal sources include umbilical cord tissue and blood, and placental tissue, all derived after birth with no harm to fetus.

Do mesenchymal stem cells have DNA?

Mesenchymal stem cells contain DNA from the host source. Our stem cells are in a consisitet state of renewal and replenishment and can be found in every tissue in our bodies. Our genetic components play a role in the quality of stem cells and the efficiency of turn over. MSC genetic stability has the potential to influence the transformation and the therapeutic effect of these MSCs

How do mesenchymal stem cells differentiate?

Mesenchymal stem cells differentiate depending on the tissue they are implanted into. MSCs are able to read the environment of the damaged tissue and begin dividing to form progenitor cell lineage of the cell needed. For example if the MSCs were injected into the knee joint, the purpose would be for progenitor chondrocytes to develop which will allow for regeneration of cartilage.

What are bone marrow derived mesenchymal stem cells?

Bone marrow derived mesenchymal cells are found present in the bone marrow . Most commonly extracted from the PSIS of the pelvic bone, these MSCs are extracted, processed and concentrated prior to injection into a damaged tissue. These MSCs then have the ability to repair the tissue that is damaged most commonly including cartilage bone, muscle, nerve and skin.

How much does it cost to get stem cell treatment?

The average soft of stem cell treatments can vary from patient to patient depending on complaint, severity, complexity of procedure, and amount of cells requested. Typical stem cell treatments can range between 5-15k, with a more typical range of 6-9k for most treatments.

How do they take stem cells from bone marrow?

Stem cells are taken from bone marrow through a process of bone marrow aspiration from the Posterior Superior iliac crest (PSIS). A small Jamshidi needle is used to penetrate the bone and collect Bone marrow Aspirate which is then concentrated prior to reinfection.

How many stem cells are in bone marrow?

An average of 30- 60 million stem cells are typically present in

Can cancer be healed by stem cells?

There is no evidence to support the statement that mesenchymal stem cells can heal cancer but hematopoietic stem cells found in bone marrow have been used for years in the treatment of leukemia and other congenital diseases of the blood cells.

What are the Benefits of Bone Marrow Derived Stem Cells?

Bone marrow derived stem cells can be very beneficial for certain conditions that affect the musculoskeletal, autoimmune, and metabolic systems. Bone marrow was one of the first sources of mesenchymal stem cells discovered, meaning they have a long and documented history of use in regenerative medicine. Additionally, they can be combined with adipose-derived stem cells for further effectiveness in certain circumstances. Your experienced stem cell provider can discuss these specific conditions in detail.

Schedule a Consultation

At Axis Stem Cell Institute, we believe that the path to living your best life is through a healthy body, mind, and outlook. However, chronic conditions can greatly affect your quality of life and prevent you from living an active lifestyle. In many cases, your only options can be a lifetime of medications or expensive surgery. We seek to provide the best in stem cell therapies to rejuvenate your body using your own cells and tissues so that you can regain your well-being. Our expert providers stay up-to-date on the latest in scientific research and advancement so that we can help you make the right choice for you and your body.

Stem cells derived from bone marrow can be an effective option for certain conditions. To schedule a consultation at our Seattle or St. Petersburg office by calling 206.823.0960 or filling out our online form. Our patient coordinators can guide you through the booking process to schedule a consultation with our stem cell experts.

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