Exosomes

Choosing between stem cells and exosomes depends on each patients’ needs and symptoms. Exosomes are acellular and act as Stem cell recruiters, which differ from the cellular mesenchymal stem cell. Indication for either depends on the patient’s presentation, biogenetic makeup, and therapy plan. Both Exosomes and Stem cells can also be used in combination. It is best to consult with a provider regarding the best option for you.

No Exosome products are approved in the US yet. Exosomes are currently in phase 2 research trials seeking FDA approval to become an investigational new drug. It is important that Exosomes are harvested and bottled in an FDA regulated GMP facility where sterility is maintained. This is an important question to ask your provider prior to booking your procedure.

Generally speaking, exosomes treatments pose very little risk and offer a great number of healing abilities. Before your exosome treatment at Axis Stem Cell Institute, our team of experts will carefully evaluate your health to determine whether exosome treatment is safe and recommended for you.

Exosomes are a type of extracellular vesicle that are released by stem cells. Exosomes are not the same as stem cells; rather, they signal stem cell activity and act as stem cell recruiters.

Exosomes are comprised of over 100 different growth factors and thousands of regulatory proteins that assist in cell signaling and recruit the bodys innate healing abilities. Exosomes contain angiogenic growth factors like VEGF which stimulate new blood influx to the area of injury. Fibroblastic growth factors such as FGF and bFGF stimulate collagen and elastin production to create new tissue and repair whats damaged. Exosomes can transfer molecules from one cell to another cell via membrane vesicle trafficking

Exosome therapy provides a regenerative non-surgical, non-medicinal option for treating wounds, injury, and disease. As exosomes work to decrease inflammation, repair tissue, and modulate disease, the longevity of the improvements is measured on a case by case basis. There are often times that we will have patients that are completely remediated by an exosome treatment and others that opt for multiple.

Exosomes were first discovered in 1983 by Stahl and group and Johnstone and group in which they were understood as a type of signaling reticulocyte found in a mammal and later labeled as an ‘exosome” by Johnstone and group in 1987.

Exosomes are acellular microvesicles isolated from Mesenchymal stem cells that have been derived from bone marrow or perinatal tissue.

Exosomes are reparative products that can be injected into the body by way of IV, intramuscular, intraarticular, in the spinal canal to access the CNS, or into the tissue to stimulate a healing cascade. Exosomes are acellular microvesicles isolated from Mesenchymal stem cells. These exosomes can be derived from MSCs harvested from Bone marrow or perinatal tissue and are used for many different diseases and conditions.

Exosomes are made of messenger and micro RNA used in the cell to cell communication. Exosomes are surrounded by a membrane but do not contain a nucleus and do not complete any metabolic processes. These vesicles are composed of thousands of signaling proteins and over 100 different types of growth factors.

Exosomes carry molecules and nutrients between cells and act as signaling vesicles in order to simulate a healing cascade and promote regenerative processes. They contain mRNA but do not contain DNA or cell-like structures.

Exosomes can only be seen with the use of a proton microscope and can be visualized as small vesicles that contain a membrane. These vesicles are approximately 1/1000th the size of an actual cell.

Exosomes have been widely used in the regenerative medicine market for the regeneration of hair follicles in patients suffering from hair loss. A combination of injection and microneedling is used to create a micro-injury to the scalp and stimulate the healing cascade and in turn repair and regenerate damaged follicles.

Exosomes are reparative products that can be used as a non-surgical, non-medicinal therapy to stimulate regeneration. Exosomes are injected into the body by way of IV, intramuscular, intraarticular, in the spinal canal to access the CNS, or into the tissue to stimulate a healing cascade. Exosomes are acellular microvesicles isolated from Mesenchymal stem cells. These exosomes can be derived from MSCs harvested from Bone marrow or perinatal tissue and are used for many different diseases and conditions.

Exosomes are micro extracellular vesicles produced in the endosomal compartments of most eukaryotic cells and once secreted are referred to as exosomal, or exosomes. They can be found in biological fluid like blood, urine, and Cerebrospinal fluid.

Exosomes are a safe non-surgical, non-medicinal option for treatment for patients seeking help with chronic disease, joint pain, arthritis, and neurodegenerative conditions among many others.

After a thorough consultation with your medical provider, if exosomes are indicated, they will be ordered and shipped to the clinic at which they will be administered. You must be a board-certified medical provider to order and inject exosomes.

Once injected into the area of need, exosomes will begin to work immediately by modulating inflammation and stimulating the healing cascade. Your medical provider will be able to give you a proper healing timeline depending on your condition and severity.

There has been no evidence thus far of cancer promotion or proliferation as a result of the use of exosome therapy. It is important to consult with a licensed medical provider to discuss pertinent medical history and be sure exosomes are the safest most effective option for your condition.

Exosomes are priced per vial. Depending on the size of the vial indicated prices may vary. After consultation with a medical provider, you will be given a recommendation of the number of exosomes needed and the cost. Each therapy plan is tailored specifically to each individual patient so it is important to get a personal assessment.

Exosomes are reparative products that can be used as a non-surgical, non-medicinal therapy to stimulate regeneration and healing. Exosomes are acellular microvesicles isolated from Mesenchymal stem cells. These exosomes can be derived from MSCs harvested from Bone marrow or perinatal tissue and are used for many different diseases and conditions. Exosomes are injected into the body by way of IV for systemic conditions, intramuscular to repair tissue, intraarticular to stimulate cartilage growth and repair, into the spinal canal to access the CNS, or into soft tissue to stimulate a healing cascade. Exosomes can be used for many different conditions including but not limited to joint pain, arthritis, sports injuries, hair regrowth, sexual dysfunction, MS, concussion, Neurodegenerative disease, and chronic pain.

Exosomes measure at approximately 30nm-150nm in size, which is about 1/1000th of cell size.

Published Peer-reviewed studies have discussed that Bone Marrow derived exosomes have a higher yield of growth and signaling factor concentration when compared to perinatal tissue. Both bone marrow-derived exosomes and perinatal derived exosomes seem to deliver a favorable outcome for the repair of tissue and inflammatory modulation.

Both Bone marrow-derived exosomes and perinatal derived exosomes have proven to yield a favorable outcome in patients looking to repair tissue, modulate inflammation, and recruit stem cell activity.